Are your students struggling to understand cells, organelles, and cell processes while reading science text?
Help students strengthen science reading comprehension and build stronger explanations using evidence with these cells and cell processes reading comprehension worksheets.
This print and go resource makes it easy to add meaningful science literacy practice to your Grade 6 NGSS life science unit with no prep required.
This resource supports Grade 6 students as they read, analyze, and apply information about cells and how they function.
Designed to align with NGSS expectations, these worksheets focus on helping students understand key cell concepts such as organelles, cell membranes, transport, energy production, protein synthesis, communication between cells, and the cell cycle.
Each reading passage is paired with questions that require students to think critically, return to the text, and use evidence to support their answers. This makes the resource ideal for building content knowledge while strengthening science literacy skills.
Students read clear, grade appropriate informational text and respond to a variety of question types.
The passages are written to support upper elementary and middle school learners and introduce academic vocabulary in context. Questions include multiple choice and true or false items that check understanding of main ideas, details, vocabulary, and scientific processes.
A cloze passage option is included to support differentiation, intervention, and learners who benefit from additional scaffolding.
✅ 3 Reading Comprehension Worksheets
Each worksheet includes 3 reading passages and 25 comprehension questions. In total, students complete 9 reading passages and respond to 75 questions across the set.
✅ 1 Cloze Passages Worksheet
A fill in the blank version of the reading content to support differentiation, review, or intervention.
✅ TOTAL: 4 Print Ready Worksheets
✅ Answer Sheets Included for Every Worksheet
Complete answer keys are provided to save time and support quick grading or self checking.
Ready to print and use immediately. No editing required.
The reading passages cover essential Grade 6 life science concepts.
Students read about cells as the basic units of life and learn how organelles work together to support cell function. Topics include the role of the nucleus, mitochondria, ribosomes, endoplasmic reticulum, Golgi apparatus, and cell membrane.
Passages also explain selective permeability, homeostasis, passive and active transport, and why energy is required for certain processes. Additional readings focus on cellular respiration, ATP, protein synthesis, cell communication, signaling molecules, and the stages of the cell cycle including interphase and mitosis.
These topics closely align with NGSS life science standards and classroom instruction.
✅ Skills Students Practice
• Science reading comprehension
• Understanding key life science vocabulary
• Analyzing information from informational text
• Using evidence from text to support explanations
• Explaining cell structure and function
• Describing how organelles work together
• Understanding cell processes such as transport, energy production, and communication
• Building confidence with NGSS aligned science content
This resource helps students move beyond memorization.
Instead of simply labeling diagrams, students read about how cells actually work and explain why processes occur. The questions require students to return to the text, identify evidence, and connect ideas across sentences and paragraphs.
This supports classroom goals related to written explanations, claim evidence reasoning strategies, and content based literacy.
✔ Classwork or independent practice
✔ Review and test preparation
✔ Science literacy stations
✔ Sub plans or emergency plans
✔ Small group instruction or intervention
✔ Early finisher activities
✔ Differentiation using the cloze worksheet for additional support
Teachers appreciate how flexible this resource is.
Use one worksheet as a quick check for understanding, or assign all four as part of a complete cells and cell processes unit.
The consistent format helps students know what to expect, while the variety of passages keeps learning focused on different aspects of cell biology. Because answer sheets are included, this resource works well for self checking, partner work, or fast grading.
This resource fits easily into existing NGSS aligned curriculum.
The content supports Grade 6 life science instruction related to structure and function, systems within organisms, and the flow of matter and energy.
It pairs well with hands on labs, modeling activities, and discussions about how cells contribute to the survival and growth of organisms. Teachers can use these worksheets before instruction to build background knowledge or after instruction to reinforce learning.
• Includes complete answer sheets for all four worksheets
• Designed for Grade 6 NGSS life science
• Appropriate for upper elementary and middle school classrooms
If you are looking for a reliable, standards aligned way to build science reading comprehension while teaching cells and cell processes, this resource provides clear text, meaningful questions, and ready to use worksheets that fit seamlessly into your classroom routine.
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